amobarbital

amobarbital; amylobarbitone; amytal; 5-ethyl-5-isopentylbarbituric acid; 5-ethyl-5-(3-methylbutyl)-1,3-diazinane-2,4,6-trione; inmetal
Links:	📏 NIST, 📖 PubMed
MeSH:	Central Nervous System Agents; GABA Modulators; Neurotransmitter Agents
CAS RN:	[57-43-2]
Formula:	C11H18N2O3; 226.28 g/mol
InChiKey:	VIROVYVQCGLCII-UHFFFAOYSA-N
SMILES:	CCC1(CCC(C)C)C(=O)NC(=O)NC1=O
Toxicology (LD50):	120 mg/Kg (cat, ip); 55.0 mg/Kg(cat, iv); 74.0 mg/Kg(cat, iv); 110 mg/Kg(cat, or); 60.0 mg/Kg(dog, iv); 112 mg/Kg(dog, or); 125 mg/Kg(dog, or); 200 mg/Kg(frog, iv); 110 mg/Kg(frog, sc); 120 mg/Kg(guinea~pig, ip); 81.0 mg/Kg(guinea~pig, iv); 170 mg/Kg(guinea~pig, sc); 200 mg/Kg(mouse, ip); 205 mg/Kg(mouse, ip); 280 mg/Kg(mouse, ip); 135 mg/Kg(mouse, iv); 200 mg/Kg(mouse, sc); 91.0 mg/Kg(rabbit, ip); 120 mg/Kg(rabbit, ip); 575 mg/Kg(rabbit, or); 150 mg/Kg(rabbit, sc); 115 mg/Kg(rat, ip); 180 mg/Kg(rat, ip); 91.0 mg/Kg(rat, iv); 400 mg/Kg(rat, or); 190 mg/Kg(rat, sc); 230 mg/Kg(rat, sc)
Melting point:	157 °C
Log10 partition octanol / water:	2.07

Isomers

4-(3-amino-2-oxoazetidinonyl-1)methylcyclohexanecarboxylic acid

amobarbital

5-ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione

5-ethyl-5-pentyl-1,3-diazinane-2,4,6-trione

pilocarpic acid